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2′-O,4′-C-Methylenecytidine

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Products Details

Product Description

– 2′-O,4′-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2′-O,4′-C-Methylenecytidine can be used to synthesize oligonucleotides. 2′-O,4′-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands[1][2].

Web ID

– HY-W570888

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C10H13N3O5

References

– [1]bicyclic nucleoside analogue, N-type conformation, synthesize oligonucleotides, duplexes|[2]Obika S, et, al. Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides. Tetrahedron Letters. 1998 Jul 23; 39(30):5401-04.

CAS Number

– 206055-69-8

Molecular Weight

– 255.23

Compound Purity

– 98.59

SMILES

– OC[C@]1(CO2)[C@@H](O)[C@@H]2[C@H](N3C=CC(N)=NC3=O)O1

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Nucleoside Antimetabolite/Analog

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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