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2′-O,4′-C-Methylenecytidine
SKU
HY-W570888-100 mg
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage, Nucleoside Antimetabolite/Analog
$50 – $120
Products Details
Product Description
– 2′-O,4′-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2′-O,4′-C-Methylenecytidine can be used to synthesize oligonucleotides. 2′-O,4′-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands[1][2].
Web ID
– HY-W570888
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C10H13N3O5
References
– [1]bicyclic nucleoside analogue, N-type conformation, synthesize oligonucleotides, duplexes|[2]Obika S, et, al. Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides. Tetrahedron Letters. 1998 Jul 23; 39(30):5401-04.
CAS Number
– 206055-69-8
Molecular Weight
– 255.23
Compound Purity
– 98.59
SMILES
– OC[C@]1(CO2)[C@@H](O)[C@@H]2[C@H](N3C=CC(N)=NC3=O)O1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.