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2′-O-MOE-rC
$50 – $100
Products Details
Product Description
– 2′-O-MOE-rC is a 2′-O-MOE modified nucleoside. 2′-O-MOE-rC can be used for synthesis of DNA[1][2].
Web ID
– HY-W570885
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C49H58N5O10P
References
– [1]Prakash TP, et al. Comparing in vitro and in vivo activity of 2′-O-[2-(methylamino)-2-oxoethyl]- and 2′-O-methoxyethyl-modified antisense oligonucleotides. J Med Chem. 2008 May 8;51(9):2766-76.|[2]Li M, et al. Synthesis and cellular activity of stereochemically-pure 2′-O-(2-methoxyethyl)-phosphorothioate oligonucleotides. Chem Commun (Camb). 2017 Jan 3;53(3):541-544.
CAS Number
– 251647-54-8
Molecular Weight
– 907.99
Compound Purity
– 98.0
SMILES
– COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OCCOC)[C@H](N5C(N=C(NC(C6=CC=CC=C6)=O)C=C5)=O)O4
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Oligonucleotides
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
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