Download Files:
Products Details
Product Description
– 2-MPMDQ is a potent and selective α1-adrenoceptor (Ki=0.37 nM) antagonist over α2-adrenoceptor (Ki=1740 nM). 2-MPMDQ is potent anti-hypertensive agent and has the potential for hypertension research[1].
Web ID
– HY-101061
Shipping
– Room temperature
Molecular Formula
– C23H27N5O2
References
– [1]J W Chern, et al. Studies on quinazolines. 5. 2,3-dihydroimidazo[1,2-c]quinazoline derivatives: a novel class of potent and selective alpha 1-adrenoceptor antagonists and antihypertensive agents. J Med Chem. 1993 Jul 23;36(15):2196-207.
CAS Number
– 149847-77-8
Molecular Weight
– 405.49
SMILES
– O=C1N(C)C2=C(C=CC=C2)C3=NC(CN4CCN(C5=CC=CC=C5OC)CC4)CN13
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor
Isoform
– α adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
