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2-Iodomelatonin
$50 – $420
Products Details
Product Description
– 2-Iodomelatonin is a potent agonist of melatonin receptor 1 (MT1) with a Ki value of 28 pM, it is more 5-fold selective for MT1 over MT2[1]. 2-iodomelatonin can be used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues[1].
Web ID
– HY-101176
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C13H15IN2O2
References
– [1]Tomkinson A, et al. A murine IL-4 receptor antagonist that inhibits IL-4- and IL-13-induced responses prevents antigen-induced airway eosinophilia and airway hyperresponsiveness. J Immunol. 2001 May 1;166(9):5792-800.|[2]Wang X, et al. The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity.J Neurosci. 2011 Oct 12;31(41):14496-507.
CAS Number
– 93515-00-5
Molecular Weight
– 358.17
Compound Purity
– 99.04
SMILES
– CC(NCCC1=C(I)NC2=C1C=C(OC)C=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMF : 30 mg/mL (ultrasonic;warming)|DMSO : 30 mg/mL (ultrasonic;warming)|Ethanol : 20 mg/mL (ultrasonic;warming)
Target
– Melatonin Receptor
Isoform
– MT1
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
