2′-Deoxyuridine-d2

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Products Details

Product Description

– 2′-Deoxyuridine-d2 is the deuterium labeled 2′-Deoxyuridine. 2′-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2′-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]

Web ID

– HY-D0186S4

Shipping

– Room temperature

Molecular Formula

– C9H10D2N2O5

References

– [1]Reidy JA, et al. Deoxyuridine increases folate-sensitive fragile site expression in human lymphocytes. Am J Med Genet. 1987 Jan;26(1):1-5.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

CAS Number

– 478511-30-7

Molecular Weight

– 230.21

SMILES

– O=C1N(C=CC(N1)=O)[C@]2([H])O[C@@H]([C@H](C2)O)C([2H])([2H])O

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Endogenous Metabolite;Isotope-Labeled Compounds

Pathway

– Metabolic Enzyme/Protease;Others

Product type

– Isotope-Labeled Compounds

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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