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Products Details
Product Description
– 2′-Deoxy-5′-O-DMT-N4-Fmoc-5-methylcytidine 3′-CE-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Web ID
– HY-152979
Shipping
– Room temperature
Molecular Formula
– C55H60N5O9P
References
– [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.
CAS Number
– 176755-87-6
Molecular Weight
– 966.07
SMILES
– O=C1N=C(NC(OCC2C3=C(C=CC=C3)C4=C2C=CC=C4)=O)C(C)=CN1[C@H]5C[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](COC(C6=CC=CC=C6)(C7=CC=C(OC)C=C7)C8=CC=C(OC)C=C8)O5
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
