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Products Details
Product Description
– 2′-Deoxy-2′-fluoroadenosine 5′-triphosphate tetralithium is an ATP analog, it exerted a strong but mixed-type inhibition on poly(AU) synthesis.
Web ID
– HY-136649
Shipping
– Room temperature
Molecular Formula
– C10H11FLi4N5O12P3
References
– [1]Kasuya T, et, al. Highly accurate synthesis of the fully 2′-fluoro-modified oligonucleotide by Therminator DNA polymerases. Bioorg Med Chem Lett. 2014 May 1; 24(9): 2134-6.|[2]Ishihama A, Enami M, Nishijima Y, Fukui T, Ohtsuka E, Ikehara M. 2′-Deoxy-2′-azidoadenosine triphosphate and 2′-deoxy-2′-fluoroadenosine triphosphate as substrates and inhibitors for Escherichia coli DNA-dependent RNA polymerase. J Biochem. 1980;87(3):825-830.
Molecular Weight
– 532.90
SMILES
– F[C@@H]([C@@H]1N2C3=C(C(N)=NC=N3)N=C2)[C@H](O)[C@H](O1)COP(OP(OP(O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
