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2′-O-(2-Methoxyethyl)guanosine
$25 – $70
Products Details
Product Description
– 2′-O-(2-Methoxyethyl)guanosine (2′-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA[1][2].
Web ID
– HY-23789
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Molecular Formula
– C13H19N5O6
References
– [1]McPherson AK, et, al. An Improved Process for the Manufacture of 5′-O-(4,4′-Dimethoxytrityl)-N2-isobutyryl-2′-O-(2-methoxyethyl)guanosine. Org. Process Res. Dev. 2020, 24, 11, 2583-2590.|[2]Saleh AF, et, al. 2′-O-(2-Methoxyethyl) Nucleosides Are Not Phosphorylated or Incorporated Into the Genome of Human Lymphoblastoid TK6 Cells. Toxicol Sci. 2018 May 1;163(1):70-78.
CAS Number
– 473278-54-5
Molecular Weight
– 341.32
Compound Purity
– 99.81
SMILES
– O[C@H]1[C@@H](OCCOC)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1CO
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage
Product type
– Biochemical Assay Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
