Download Files:
18-Deoxyherboxidiene
$3,790
Only 1000 item(s) left in stock.
Products Details
Product Description
– 18-Deoxyherboxidiene (RQN-18690A) is a potent angiogenesis inhibitor. 18-Deoxyherboxidiene targets SF3b, a spliceosome component that is a subcomplex of the U2 small nuclear ribonucleoprotein (snRNP) in the spliceosome. 18-Deoxyherboxidiene inhibits the migration and tube formation of human umbilical vein endothelial cells (HUVECs) without significant cell toxicity. 18-Deoxyherboxidiene has the potential for cancer research[1].
Web ID
– HY-133924
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H42O5
References
– [1]Hideaki Kakeya, et al. RQN-18690A (18-deoxyherboxidiene) targets SF3b, a spliceosome component, and inhibits angiogenesis. J Antibiot (Tokyo). 2016 Feb;69(2):121-3.
CAS Number
– 1200128-66-0
Molecular Weight
– 422.60
SMILES
– C[C@]1([C@]([C@@H]([C@H](CC)OC)C)([H])O1)C[C@H](C)/C=C/C=C(C)/[C@@H]2[C@@H](C)CC[C@H](CC(O)=O)O2
Clinical Information
– No Development Reported
Research Area
– Cancer; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Others
Pathway
– Others
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
