Products Details

Product Description

– 17-DMAP-GA, a Geldanamycin (HY-15230) analogue, is an inhibitor of HSP90. 17-DMAP-GA causes cell cycle abnormalities[1][2].

Web ID

– HY-136312

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C33H50N4O8

References

– [1]Jurczyszyn A, et al. Geldanamycin and Its Derivatives Inhibit the Growth of Myeloma Cells and Reduce the Expression of the MET Receptor. J Cancer. 2014;5(6):480-490. Published 2014 May 31.|[2]Tian ZQ, et al. Synthesis and biological activities of novel 17-aminogeldanamycin derivatives. Bioorg Med Chem. 2004;12(20):5317-5329.

CAS Number

– 169521-68-0

Molecular Weight

– 630.77

SMILES

– CN(C)CCCNC(C(C=C1NC(/C(C)=C/C=C[C@@H]2OC)=O)=O)=C(C[C@H](C[C@@H]([C@@H]([C@H](/C=C([C@@H]2OC(N)=O)C)C)O)OC)C)C1=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– HSP

Pathway

– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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