Download Files:
17-AEP-GA
SKU
HY-133570-Get quote
Category ADC Related
Tags ADC Cytotoxin;HSP, Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease, Cancer
Products Details
Product Description
– 17-AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. ADCs Toxin[1].
Web ID
– HY-133570
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C34H50N4O8
References
– [1]Katarzyna Miekus, et al. 17AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. Oncol Rep. 2012 Nov;28(5):1903-9.
CAS Number
– 75747-23-8
Molecular Weight
– 642.78
SMILES
– O=C(C(NCCN1CCCC1)=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(C)/[C@H](OC(N)=O)[C@@H](OC)/C=CC=C(C)C3=O)C=C(N3)C2=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Cytotoxin;HSP
Isoform
– HSP90;Traditional Cytotoxic Agents
Pathway
– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.