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16,16-Dimethyl prostaglandin E2
$320 – $2,650
Products Details
Product Description
– 16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway[1][2].
Web ID
– HY-106420
Storage Temperature
– Solution, -20°C, 2 years
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H36O5
References
– [1]Hagedorn EJ, et al. Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. xp Cell Res. 2014 Dec 10;329(2):220-6.|[2]Roulis M, et al. Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):E4658-67.
CAS Number
– 39746-25-3
Molecular Weight
– 380.52
Compound Purity
– 98.0
SMILES
– CCCCC(C)([C@@H](/C=C/[C@@H]1[C@@H](C/C=CCCCC(O)=O)C(C[C@H]1O)=O)O)C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Prostaglandin Receptor
Isoform
– EP
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
