Download Files:
1,4-PBIT (dihydrobromide)
$24 – $38
Products Details
Product Description
– 1,4-PBIT (1,4-PB-ITU) dihydrobromide (compound 46) is a potent nitric oxide synthases (NOS) inhibitor, with Ki values of 7.6 nM, 360 nM, and 16 nM for the inducible (iNOS), endothelial (eNOS), and neuronal (nNOS) isozymes, respectively[1].
Web ID
– HY-135224
Shipping
– Room temperature
Molecular Formula
– C12H20Br2N4S2
References
– [1]E P Garvey, et al. Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas. J Biol Chem. 1994 Oct 28;269(43):26669-76.
CAS Number
– 157254-60-9
Molecular Weight
– 444.25
SMILES
– NC(SCCC1=CC=C(CCSC(N)=N)C=C1)=N.[H]Br.[H]Br
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– NO Synthase
Isoform
– eNOS;iNOS;nNOS
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
