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1,2′-O-Dimethylguanosine

SKU HY-137406-Get quote Category Reference compound Tags Cell Cycle/DNA Damage, Nucleoside Antimetabolite/Analog, Others

Products Details

Product Description

– 1,2′-O-Dimethylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Web ID

– HY-137406

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C12H17N5O5

References

– [1]Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.

CAS Number

– 73667-71-7

Molecular Weight

– 311.29

SMILES

– OC[C@@H]1[C@@H](O)[C@@H](OC)[C@H](N(C=N2)C3=C2C(N(C)C(N)=N3)=O)O1

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– 10 mM in DMSO

Target

– Nucleoside Antimetabolite/Analog

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.