11α-O-Tigloyl-12β-O-acetyltenacigenin B

Products Details

Product Description

– 11α-O-Tigloyl-12β-O-acetyltenacigenin B is an ester derivative of Tenacigenin B (HY-N1168), which is isolated from Garcinia cambogia (MTC). Tenacigenin B modulates the antitumor effects of Aurora-A in lymphoma.

Web ID

– HY-N12436

Shipping

– Room temperature

Molecular Formula

– C28H40O7

References

– [1]Dai X, et al.Tenacigenin B Has Anti-Tumor Effect in Lymphoma by In Vitro and In Vivo Study. Med Sci Monit. 2019 Sep 1;25:6563-6573.|[2]Zhu RJ, et al.Total aglycones from Marsdenia tenacissima increases antitumor efficacy of paclitaxel in nude mice. Molecules. 2014 Sep 5;19(9):13965-75.

CAS Number

– 154022-51-2

Molecular Weight

– 488.61

SMILES

– C[C@@]12[C@]3(CC[C@H]2C(C)=O)[C@]4([C@]([C@@]5([C@@](C[C@H](CC5)O)([H])CC4)C)([H])[C@@H]([C@H]1OC(C)=O)OC(/C(C)=C/C)=O)O3

Clinical Information

– No Development Reported

Research Area

– cancer

Solubility

– 10 mM in DMSO

Target

– Aurora Kinase

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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