Download Files:
11α-O-Tigloyl-12β-O-acetyltenacigenin B
SKU
HY-N12436-Get quote
Category Reference compound
Tags Aurora Kinase, Cancer, Cell Cycle/DNA Damage;Epigenetics
Products Details
Product Description
– 11α-O-Tigloyl-12β-O-acetyltenacigenin B is an ester derivative of Tenacigenin B (HY-N1168), which is isolated from Garcinia cambogia (MTC). Tenacigenin B modulates the antitumor effects of Aurora-A in lymphoma.
Web ID
– HY-N12436
Shipping
– Room temperature
Molecular Formula
– C28H40O7
References
– [1]Dai X, et al.Tenacigenin B Has Anti-Tumor Effect in Lymphoma by In Vitro and In Vivo Study. Med Sci Monit. 2019 Sep 1;25:6563-6573.|[2]Zhu RJ, et al.Total aglycones from Marsdenia tenacissima increases antitumor efficacy of paclitaxel in nude mice. Molecules. 2014 Sep 5;19(9):13965-75.
CAS Number
– 154022-51-2
Molecular Weight
– 488.61
SMILES
– C[C@@]12[C@]3(CC[C@H]2C(C)=O)[C@]4([C@]([C@@]5([C@@](C[C@H](CC5)O)([H])CC4)C)([H])[C@@H]([C@H]1OC(C)=O)OC(/C(C)=C/C)=O)O3
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Aurora Kinase
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.