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Products Details
Product Description
– 11β-HSD2-IN-1 (compound CDSN) is a potent inhibitor of 11β-HSD2, inhibiting the metabolism of Cholestane-3β,5α,6β-triol (CT) in cells by 11β-HSD2 into the tumor promoter, carcinosterone. 11β-HSD2-IN-1 inhibits testosterone biosynthesis, thereby inhibiting MCF-7 cell proliferation. 11β-HSD2-IN-1 has immune activity and antiviral infection effects[1].
Web ID
– HY-157161
Shipping
– Room temperature
Molecular Formula
– C27H48O5S
References
– [1]de Médina P et al. Chemical synthesis and biochemical properties of cholestane-5α,6β-diol-3-sulfonate: A non-hydrolysable analogue of cholestane-5α,6β-diol-3β-sulfate. J Steroid Biochem Mol Biol. 2023 Nov;234:106396.
Molecular Weight
– 484.73
SMILES
– CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])C[C@@H](O)[C@@]4(O)C[C@@H](S(=O)(O)=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– 11β-HSD
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
