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Products Details
Product Description
– 10-DEBC is a selective Akt inhibitor. 10-DEBC shows strong inhibitory activity against Moloney murine leukemia virus (Pim) kinase-1 (IC50=1.28 μM)[1].
Web ID
– HY-133850
Shipping
– Room temperature
Molecular Formula
– C20H25ClN2O
References
– [1]Li, W., et al. More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors. Med. Chem. Commun. 2014;5(4):507–511.
CAS Number
– 201788-90-1
Molecular Weight
– 344.88
SMILES
– CCN(CC)CCCCN1C2=C(C=CC=C2)OC3=CC=C(Cl)C=C13
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Pim
Pathway
– JAK/STAT Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
