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1-Methyl-2-nonyl-4(1H)-quinolone
SKU
HY-N1636-Get quote
Category Natural Products
Tags Monoamine Oxidase, Neurological Disease, Neuronal Signaling
Products Details
Product Description
– 1-Methyl-2-nonyl-4(1H)-quinolone, a quinolone alkaloid, is a potent and selective MAO-B (monoamine oxidase) inhibitor. 1-Methyl-2-nonyl-4(1H)-quinolone exhibites inhibitory activity on leukotriene biosynthesis, with an IC50 of 12.1 μM[1][2].
Web ID
– HY-N1636
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C19H27NO
References
– [1]Han XH, et al. Quinolone alkaloids from evodiae fructus and their inhibitory effects on monoamine oxidase. Arch Pharm Res. 2007 Apr;30(4):397-401.|[2]Adams M, et al. Inhibition of leukotriene biosynthesis by quinolone alkaloids from the fruits of Evodia rutaecarpa. Planta Med. 2004 Oct;70(10):904-8.
CAS Number
– 68353-24-2
Molecular Weight
– 285.42
SMILES
– O=C1C=C(CCCCCCCCC)N(C)C2=C1C=CC=C2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Monoamine Oxidase
Isoform
– MAO-A;MAO-B
Pathway
– Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.