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1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one
SKU
HY-W354644-Get quote
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage, Nucleoside Antimetabolite/Analog
Size – Get quote
Products Details
Product Description
– 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Web ID
– HY-W354644
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C10H12N2O7
References
– [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
CAS Number
– 59892-36-3
Molecular Weight
– 272.21
SMILES
– OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(C=CC([N+]([O-])=O)=C2)=O)O1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.