1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one

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Product Description

– 1-(β-D-Ribofuranosyl)-5-nitropyrine-2(1H)-one is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Web ID

– HY-W354644

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C10H12N2O7

References

– [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

CAS Number

– 59892-36-3

Molecular Weight

– 272.21

SMILES

– OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(C=CC([N+]([O-])=O)=C2)=O)O1

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Nucleoside Antimetabolite/Analog

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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