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1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione
SKU
HY-154663-Get quote
Category Oligonucleotides
Tags Cancer, Cell Cycle/DNA Damage, Nucleoside Antimetabolite/Analog
Products Details
Product Description
– 1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Web ID
– HY-154663
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C9H11BrN2O6
References
– [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
CAS Number
– 3370-69-2
Molecular Weight
– 323.10
SMILES
– OC[C@@H]1[C@@H](O)[C@H](O)[C@H](N2C(NC(C(Br)=C2)=O)=O)O1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.