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Product Description
– β2AR agonist 2(compound 8a) is a β2 -Adrenergic receptor (β2AR) agonist. β2AR agonist 2 is a saturated nitrogen ring compound containing 4- to 7-membered heterocycle. β2AR agonist 2 has a chiral structure (the -R form) by carrying carbon containing the essential hydroxyl, thereby enhancing cellular glucose uptake (GU) activity and significantly stimulating glucose uptake by skeletal muscle cells. β2AR agonist 2 can be used in the study of Type 2 Diabetes (T2D)[1].
Web ID
– HY-149727
Shipping
– Room temperature
Molecular Formula
– C13H18FNO
References
– [1]Jaunsleine K, et al. Development of novel β2-adrenergic receptor agonists for the stimulation of glucose uptake – The importance of chirality and ring size of cyclic amines. Bioorg Med Chem Lett. 2023 Nov 13:129562.
Molecular Weight
– 223.29
SMILES
– FC1=CC=CC([C@@H](O)[C@@]2([H])C[C@@H](CCC)N2)=C1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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