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Products Details
Product Description
– (±)-Naproxen-13C,d3 is the deuterium and 13C labeled (±)-Naproxen[1]. (±)-Naproxen ((Rac)-Naproxen) is a racemate of Naproxen (HY-15030). Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively.
Web ID
– HY-15029S2
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C13 13CH11D3O3
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
CAS Number
– 1261392-52-2
Molecular Weight
– 234.27
SMILES
– OC(C(C1=CC2=C(C=C1)C=C(C=C2)O[13C]([2H])([2H])[2H])C)=O
Clinical Information
– No Development Reported
Solubility
– 10 mM in DMSO
Target
– COX
Pathway
– Immunology/Inflammation
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
