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Products Details
Product Description
– (±)-HIP-B is a non-competitive excitatory amino acid transporter (EAAT) blocker that effectively blocks Glu uptake (IC50=17-18 μM). (±)-HIP-B is also a lead compound against ischemia-induced neuronal degeneration. (±)-HIP-B can be used in the study of neurological diseases[1].
Web ID
– HY-107524
Shipping
– Room temperature
Molecular Formula
– C6H8N2O4
References
– [1]Andrea Pinto, et al. Synthesis of enantiomerically pure HIP-A and HIP-B and investigation of their activity as inhibitors of excitatory amino acid transporters.
CAS Number
– 227619-65-0
Molecular Weight
– 172.14
SMILES
– OC([C@@H]1[C@]2([H])[C@@](CN1)([H])C(NO2)=O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– EAAT
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
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