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β-catenin-IN-7
Products Details
Product Description
– β-catenin-IN-7 (Compound 9) is a β-catenin inhibitor. β-catenin-IN-7 inhibits the interaction between β-catenin and Tcf-4, and inhibits Wnt-dependent target gene expression. β-catenin-IN-7 has anti-cancer activity[1].
Web ID
– HY-149858
Shipping
– Room temperature
Molecular Formula
– C17H13BrN2O2S
References
– [1]Nalli M, et al. Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent. ACS Pharmacol Transl Sci. 2023 Jul 3;6(7):1087-1103.
Molecular Weight
– 389.27
SMILES
– O=S(C1=CC=C(Br)C=C1)(NC2=CC=C(C3=NC=CC=C3)C=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Wnt
Pathway
– Stem Cell/Wnt
Product type
– Reference compound
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