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Imidaprilate

$695

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Products Details

Product Description

– Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC50 of 2.6 nM, and is used in the research of hypertensive disease.

Web ID

– HY-109592

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C18H23N3O6

References

– [1]Kubo M, et al. Pharmacological studies on (4S)-1-methyl-3-[(2S)-2-[N-((1S)-1-ethoxycarbonyl-3-phenylpropyl)amino] propionyl]-2-oxo-imidazolidine-4-carboxylic acid hydrochloride (TA-6366), a new ACE inhibitor: I. ACE inhibitory and anti-hypertensive activities. Jpn J Pharmacol. 1990 Jun;53(2):201-10.

CAS Number

– 89371-44-8

Molecular Weight

– 377.39

SMILES

– O=C([C@H](CN1C)N(C([C@@H](N[C@H](C(O)=O)CCC2=CC=CC=C2)C)=O)C1=O)O

Clinical Information

– Launched

Research Area

– Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– Angiotensin-converting Enzyme (ACE)

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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