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Drotaverine (hydrochloride)
$60 – $550
Products Details
Product Description
– Drotaverine (hydrochloride) is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC) blocker, blocks the degradation of 3′,5′-cyclic adenosine monophosphate. Drotaverine (hydrochloride) exhibits in vivo antispasmodic efficacy without anticholinergic effects.
Web ID
– HY-108974
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C24H32ClNO4
References
– [1]Patai Z, Guttman A, Mikus EG. Assessment of the Airway Smooth Muscle Relaxant Effect of Drotaverine. Pharmacology. 2018;101(3-4):163-169.
CAS Number
– 985-12-6
Molecular Weight
– 433.97
Compound Purity
– 99.48
SMILES
– CCOC1=CC2=C(C=C1OCC)CCN/C2=CC3=CC=C(OCC)C(OCC)=C3.[H]Cl
Clinical Information
– Launched
Solubility
– H2O : 100 mg/mL (ultrasonic)
Target
– Calcium Channel;Phosphodiesterase (PDE)
Isoform
– L-type calcium channel;PDE4
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
