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Ro 8-4304 (hydrochloride)

Products Details

Product Description

– Ro 8-4304 hydrochloride is a potent NMDA receptor antagonist. Ro 8-4304 hydrochloride is a NR2B selective, non-competitive, voltage-independent antagonist[1].

Web ID

– HY-107716

Shipping

– Room temperature

Molecular Formula

– C21H24ClFN2O3

References

– [1]Kew JN, et, al. State-dependent NMDA receptor antagonism by Ro 8-4304, a novel NR2B selective, non-competitive, voltage-independent antagonist. Br J Pharmacol. 1998 Feb;123(3):463-72.

CAS Number

– 1312991-77-7

Molecular Weight

– 406.88

SMILES

– NC(C(C=C1)=CC=C1OCC(O)CN2CCC(C3=CC=C(F)C=C3)=CC2)=O.Cl

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– iGluR

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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