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Products Details
Product Description
– SR-3576 is a highly potent and selective JNK3 inhibitor with an IC50 of 7 nM[1].
Web ID
– HY-107596
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C27H27N5O5
References
– [1]Kamenecka T, et al. Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38. J Biol Chem. 2009 May 8;284(19):12853-61.
CAS Number
– 1164153-22-3
Molecular Weight
– 501.53
SMILES
– CC1=CC=CC(NC(NC2=CN(C3=CC(C(NC4=CC(OC)=C(OC)C(OC)=C4)=O)=CC=C3)N=C2)=O)=C1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– JNK
Isoform
– JNK3
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
