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Products Details
Product Description
– Heptaplatin (SKI 2053R) is a platinum derivative with anticancer activity against various cancer cell lines, including cisplatin-resistant tumor cell lines. SKI-2053R is active in the research of gastric adenocarcinoma and has favorable toxicity profiles[1].
Web ID
– HY-106588
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C11H20N2O6Pt
References
– [1]Kim NK, et al. Phase II clinical trial of SKI-2053R, a new platinum analog, in the treatment of patients with advanced gastric adenocarcinoma. Cancer. 1999;86(7):1109-1115.
CAS Number
– 146665-77-2
Molecular Weight
– 471.36
SMILES
– O=C(O[Pt]([NH2]C1)(O2)[NH2]C[C@@]3([H])OC(O[C@]13[H])C(C)C)CC2=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA Alkylator/Crosslinker
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
