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Products Details
Product Description
– Mivobulin (NSC 613862) is a tubulin inhibitor, binds to tubulin in the region that overlaps the colchicine site, and inhibits tubulin polymerization. Mivobulin (NSC 613862) promotes the formation of abnormal polymers and a GTPase activity in the tubulin dimer. Anti-cancer activity[1].
Web ID
– HY-106423
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C17H19N5O2
References
– [1]Barbier P, et al. The active GTP- and ground GDP-liganded states of tubulin are distinguished by the binding of chiral isomers of ethyl 5-amino-2-methyl-1,2-dihydro-3-phenylpyrido[3,4-b]pyrazin-7-yl carbamate. Biochemistry. 1998 Jan 13;37(2):758-68.
CAS Number
– 122332-18-7
Molecular Weight
– 325.37
SMILES
– O=C(OCC)NC1=CC2=C(C(N)=N1)N=C(C3=CC=CC=C3)[C@H](C)N2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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