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Dutogliptin
$550 – $1,500
Products Details
Product Description
– Dutogliptin (PHX-1149 free base) is an orally available, potent, and selective dipeptidyl peptidase-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.
Web ID
– HY-10286
Storage Temperature
– 4°C (Powder, stored under nitrogen)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C10H20BN3O3
References
– [1]Marier JF, et al. Population pharmacokinetic analysis of dutogliptin, a selective dipeptidyl peptidase-4 inhibitor. Clin Pharmacol Drug Dev. 2014 Jul;3(4):297-304.|[2]Pattzi HM, et al. Dutogliptin, a selective DPP4 inhibitor, improves glycaemic control in patients with type 2 diabetes: a 12-week, double-blind, randomized, placebo-controlled, multicentre trial. Diabetes Obes Metab. 2010 Apr;12(4):348-55.
CAS Number
– 852329-66-9
Molecular Weight
– 241.0951
Compound Purity
– 99.32
SMILES
– O=C(CN[C@@H]1CCNC1)N(CCC2)[C@@H]2B(O)O
Clinical Information
– Phase 3
Research Area
– Metabolic Disease
Solubility
– DMSO : 300 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Target
– Dipeptidyl Peptidase
Isoform
– DPP-4
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
