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Mericitabine
$225 – $1,280
Products Details
Product Description
– Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication.
Web ID
– HY-10240
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C18H26FN3O6
References
– [1]Soriano V, et al. Directly acting antivirals against hepatitis C virus. J Antimicrob Chemother. 2011 Aug;66(8):1673-86|[2]Le Pogam S, et al.
Characterization of HCV quasispecies dynamics upon short term dual-therapy with the HCV NS5B nucleoside polymerase inhibitor mericitabine and the NS3/4 protease inhibitor danoprevir.
Antimicrob Agents Chemother. 2012 Nov;56(11):5494-5|[3]Guedj J, et al.
Hepatitis C viral kinetics with the nucleoside polymerase inhibitor mericitabine (RG7128).
Hepatology. 2012 Apr;55(4):1030-7.
CAS Number
– 940908-79-2
Molecular Weight
– 399.41
Compound Purity
– 99.47
SMILES
– O=C1N=C(C=CN1[C@@H]([C@@](C)([C@@H]2OC(C(C)C)=O)F)O[C@@H]2COC(C(C)C)=O)N
Clinical Information
– Phase 2
Research Area
– Infection
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– HCV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
