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Rbin-2

SKU HY-100817-10 mg Category Tags , ,

$110$1,070

Products Details

Product Description

– Rbin-2 is a potent, reversible and selective inhibitor of Midasin (Mdn1), an enzyme belonging to the AAA+ (ATPases associated with diverse cellular activities) protein family. Rbin-2 inhibits eukaryotic ribosome biogenesis and is a powerful probe for the eukaryotic ribosome assembly[1].

Web ID

– HY-100817

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C13H11BrN4S

References

– [1]Kawashima SA, et al. Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis. Cell. 2016 Oct 6;167(2):512-524.e14.

CAS Number

– 2032282-97-4

Molecular Weight

– 335.22

Compound Purity

– 98.0

SMILES

– C=C(C)CSC1=NN=C2C(NC3=C2C=CC(Br)=C3)=N1

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– DMSO : 8.33 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Phosphatase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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