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D-Serine
$55 – $77
Products Details
Product Description
– D-Serine ((R)-Serine), an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. D-Serinee has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration[1][2].
Web ID
– HY-100808
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C3H7NO3
References
– [1]Andrea R. Durrant, et al. D-Serine in Neuropsychiatric Disorders: New Advances.|[2]MacKay MB, et al. D-Serine: Potential Therapeutic Agent and/or Biomarker in Schizophrenia and Depression? Front Psychiatry. 2019 Feb 6;10:25.|[3]Dai X, et al. D-Serine made by serine racemase in Drosophila intestine plays a physiological role in sleep. Nat Commun. 2019 May 7;10(1):1986.|[4]Suwandhi L, et al. Chronic d-serine supplementation impairs insulin secretion. Mol Metab. 2018 Oct;16:191-202.
CAS Number
– 312-84-5
Molecular Weight
– 105.09
Compound Purity
– 98.0
SMILES
– N[C@H](CO)C(O)=O
Clinical Information
– Launched
Research Area
– Neurological Disease
Solubility
– H2O : ≥ 50 mg/mL|Methanol : < 1 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Endogenous Metabolite;iGluR
Isoform
– Human Endogenous Metabolite;NMDA Receptor
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
