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TPO agonist 1
$120 – $1,440
Products Details
Product Description
– TPO agonist 1 is a thrombopoietin (TPO) agonist extracted from patent WO2008134338A1, compound TPO mimetic. It would be useful as promoters of thrombopoiesis and megakaryocytopoiesis to treat thrombocytopenia[1].
Web ID
– HY-100380
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H22N8O2
References
– [1]Jerome Francis Hayes. Novel processes of making hydroxy-1-azo-derivatives as tpo mimetics. 6 November 2008. WO2008134338A1.|[2]Siegal D et al. Thrombopoietin receptor agonists in primary immune thrombocytopenia.
et al. Semin Hematol. 2013 Jan;50 Suppl 1:S18-21
CAS Number
– 1033040-23-1
Molecular Weight
– 466.49
Compound Purity
– 98.0
SMILES
– O=C(N(C1=CC=C(C)C(C)=C1)N=C/2C)C2=NNC3=C(O)C(C4=CC=CC(C5=NN=NN5)=C4)=CC=C3
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : ≥ 36 mg/mL
Target
– Thrombopoietin Receptor
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
