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Remetinostat
SKU
HY-100365-10 mg
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;Epigenetics, HDAC
$110 – $860
Products Details
Product Description
– Remetinostat (SHP-141) is a hydroxamic acid-based inhibitor of histone deacetylase enzymes (HDAC) which is under development for the treatment of cutaneous T-cell lymphoma[1].
Web ID
– HY-100365
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H21NO6
References
– [1]Yijun Deng, et al. Process Development of the Soft Histone Deacetylate Enzyme Inhibitor SHP-141: Acylation of Methyl Paraben and Suberyl Hydroxamic Acid Formation. Org. Process Res. Dev. 2016, 20, 10, 1812-1820.
CAS Number
– 946150-57-8
Molecular Weight
– 323.34
Compound Purity
– 98.0
SMILES
– O=C(OC)C1=CC=C(OC(CCCCCCC(NO)=O)=O)C=C1
Clinical Information
– Phase 2
Research Area
– Cancer
Solubility
– DMSO : 150 mg/mL (ultrasonic)
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.