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C16-Ceramide
$55 – $460
Products Details
Product Description
– C16-Ceramide is a natural small molecule activating p53 through the direct and selective binding[1].
Web ID
– HY-100354
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C34H67NO3
References
Р[1]Fekry B, et al. C16-ceramide is a natural regulatory ligand of p53 in cellular stress response. Nat Commun. 2018 Oct 8;9(1):4149.|[2]R̩nert AF, et al. The proapoptotic C16-ceramide-dependent pathway requires the death-promoting factor Btf in colon adenocarcinoma cells. J Proteome Res. 2009 Oct;8(10):4810-22.
CAS Number
– 24696-26-2
Molecular Weight
– 537.90
Compound Purity
– 99.0
SMILES
– CCCCCCCCCCCCCCCC(N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMF : 20 mg/mL (ultrasonic;warming;heat to 60°C)|Ethanol : 20 mg/mL (warming;heat to 60°C)
Target
– Apoptosis;Endogenous Metabolite;MDM-2/p53
Pathway
– Apoptosis;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
