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MCHR1 antagonist 2
$180 – $3,200
Products Details
Product Description
– MCHR1 antagonist 2 is an antagonist of melanin concentrating hormone receptor 1, with an IC50 of 65 nM; MCHR1 antagonist 2 also inhibits hERG, with an IC50 of 4.0 nM in IMR-32 cells[1].
Web ID
– HY-100321
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C23H21FN2O5
References
– [1]Lynch JK, et al. Optimization of chromone-2-carboxamide melanin concentrating hormone receptor 1 antagonists: assessment of potency, efficacy, and cardiovascular safety. J Med Chem. 2006 Nov 2;49(22):6569-84.
CAS Number
– 863115-70-2
Molecular Weight
– 424.42
Compound Purity
– 98.27
SMILES
– O=C(C1=CC(C2=CC(F)=CC=C2O1)=O)NC3CCN(CC4=CC=C(OCO5)C5=C4)CC3
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Endocrinology
Solubility
– DMSO : 10 mg/mL (ultrasonic;adjust pH to 6 with HCl)
Target
– MCHR1 (GPR24);Potassium Channel
Pathway
– GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
