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Mivotilate

$300$2,250

Products Details

Product Description

– Mivotilate is a nontoxic, potent activator of the aryl hydrocarbon receptor (AhR), and acts as a hepatoprotective agent.

Web ID

– HY-100242

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Molecular Formula

– C12H14N2O3S3

References

– [1]Whelan F, et al. Amino acid substitutions in the aryl hydrocarbon receptor ligand binding domain reveal YH439 as an atypical AhR activator. Mol Pharmacol. 2010 Jun;77(6):1037-46.|[2]Jeong KS, et al. Transcriptional inhibition of cytochrome P4502E1 by a synthetic compound, YH439. Arch Biochem Biophys. 1996 Feb 1;326(1):137-44.|[3]Lee IJ, et al. Transcriptional induction of the cytochrome P4501A1 gene by a thiazolium compound, YH439. Mol Pharmacol. 1996 Jun;49(6):980-8.

CAS Number

– 130112-42-4

Molecular Weight

– 330.45

Compound Purity

– 99.58

SMILES

– O=C(OC(C)C)/C(C(NC1=NC(C)=CS1)=O)=C2SCS2

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Aryl Hydrocarbon Receptor

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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