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FN-439
SKU
HY-100210-Get quote
Category Reference compound
Tags Cancer; Inflammation/Immunology, Metabolic Enzyme/Protease, MMP
Products Details
Product Description
– FN-439 is a selective collagenase-1 inhibitor. FN-439 inhibits collagenase-1 with an IC50 value of 1 μM. FN-439 can be used for the research of cancer and inflammation[1][2].
Web ID
– HY-100210
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H34N6O6
References
– [1]U Benbow, et al. Human breast cancer cells activate procollagenase-1 and invade type I collagen: invasion is inhibited by all-trans retinoic acid. Clin Exp Metastasis. 1999 May;17(3):231-8.|[2]H Anan, et al. Effects of a combination of an antibacterial agent (ofloxacin) and a collagenase inhibitor (FN-439) on the healing of rat periapical lesions. J Endod. 1996 Dec;22(12):668-73.
CAS Number
– 124168-73-6
Molecular Weight
– 490.55
SMILES
– ONC([C@@H](C)NC([C@@H](CC(C)C)NC([C@H]1N(CCC1)C(CNC(C2=CC=C(C=C2)N)=O)=O)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– MMP
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.