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N-Demethyl Mifepristone

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Product Description

– N-Demethyl Mifepristone (RU 42633) is an active metabolite of Mifepristone (HY-13683). The affinities of N-Demethyl Mifepristone to the glucocorticoid receptor is 61% compared with 100% for Mifepristone[1].

Web ID

– HY-W740216

Shipping

– Room temperature

Molecular Formula

– C28H33NO2

References

– [1]Nguyen D, et al. Effects of Ketoconazole on the Pharmacokinetics of Mifepristone, a Competitive Glucocorticoid Receptor Antagonist, in Healthy Men. Adv Ther. 2017 Oct;34(10):2371-2385.

CAS Number

– 104004-96-8

Molecular Weight

– 415.57

SMILES

– C[C@@]12[C@](CC[C@@]2(O)C#CC)([H])[C@@]3([H])C([C@@H](C4=CC=C(C=C4)NC)C1)=C5C(CC3)=CC(CC5)=O

Clinical Information

– No Development Reported

Research Area

– Endocrinology

Solubility

– 10 mM in DMSO

Target

– Drug Metabolite, Glucocorticoid Receptor

Pathway

– Immunology/Inflammation, Metabolic Enzyme/Protease, Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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