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N-Acetylputrescine

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Products Details

Product Description

– N-Acetylputrescine (NAP) is an endogenous metabolite widely present in animals and plants. N-Acetylputrescine can be used as a biomarker for lung squamous cell carcinoma (SCCL) and Parkinson’s disease (PD) for disease diagnosis[1][2][3].

Web ID

– HY-W342604

Storage Temperature

– 4°C (Powder, protect from light, stored under nitrogen)

Shipping

– Room Temperature

Molecular Formula

– C6H14N2O

References

– [1]Liu R, et al. Plasma N-acetylputrescine, cadaverine and 1,3-diaminopropane: potential biomarkers of lung cancer used to evaluate the efficacy of anticancer drugs. Oncotarget. 2017 Jul 17;8(51):88575-88585. |[2]Pfanzagl B, et al. N-acetylputrescine as a characteristic constituent of cyanelle peptidoglycan in glaucocystophyte algae. J Bacteriol. 1996 Dec;178(23):6994-7. |[3]Peng K W, et al. Identification and Validation of N-Acetylputrescine in Combination With Non-Canonical Clinical Features As a Parkinson’s Disease Biomarker Panel[J]. bioRxiv, 2021: 2021.07. 23.453542.|[4]Menashe M, et al. Formulation of N-acetylputrescine and N1-acetylspermidine in cultured human lymphocytes. Biochem J. 1980 Apr 15;188(1):263-7.

CAS Number

– 5699-41-2

Molecular Weight

– 130.19

Compound Purity

– 99.56

SMILES

– CC(NCCCCN)=O

Clinical Information

– Phase 3

Research Area

– Cancer, Neurological Disease

Solubility

– DMSO : 100 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)

Target

– Endogenous Metabolite

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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