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Citric acid (trisodium)

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Products Details

Product Description

– Citric acid trisodium is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium causes renal toxicity in mice[1][2][3].

Web ID

– HY-B2201

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C6H5Na3O7

Citations

– Insect Biochem Mol Biol. 2023 May 12;103958.|Food Chem. 2022: 134807.|New J Chem. 03 Aug 2022.

References

– [1]Chen X, et al. Study on injury effect of food additive citric acid on liver tissue in mice. Cytotechnology. 2014 Mar;66(2):275-82.|[2]Chen X, Lv Q, Liu Y, Deng W. Effects of the food additive, citric acid, on kidney cells of mice. Biotech Histochem. 2015 Jan;90(1):38-44.|[3]Ying TH, et al. Citric acid induces cell-cycle arrest and apoptosis of human immortalized keratinocyte cell line (HaCaT) via caspase- and mitochondrial-dependent signaling pathways. Anticancer Res. 2013 Oct;33(10):4411-20.

CAS Number

– 68-04-2

Molecular Weight

– 258.07

Compound Purity

– 98.0

SMILES

– [Na].O=C(O)CC(O)(C(=O)O)CC(=O)O

Clinical Information

– Launched

Research Area

– Metabolic Disease

Solubility

– H2O : 50 mg/mL (ultrasonic)

Target

– Apoptosis;Endogenous Metabolite

Isoform

– Human Endogenous Metabolite

Pathway

– Apoptosis;Metabolic Enzyme/Protease

Product type

– Biochemical Assay Reagents

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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