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Products Details
Product Description
– Quinidine sulfate is an antiarrhythmic agent. Quinidine sulfate is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine sulfate is also a K+ channel blocker with an IC50 of 19.9 μM. Quinidine sulfate can be used for malaria research[1][2][3].
Web ID
– HY-B1751B
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H26N2O6S
References
– [1]Kehl SJ, et al. Quinidine-induced inhibition of the fast transient outward K+ current in rat melanotrophs. Br J Pharmacol. 1991 Jul;103(3):1807-13.|[2]Roden DM, et al. Class I antiarrhythmic agents: quinidine, procainamide and N-acetylprocainamide, disopyramide.|[3]Moody DE, et al. Quinidine inhibits in vivo metabolism of amphetamine in rats: impact upon correlation between GC/MS and immunoassay findings in rat urine. J Anal Toxicol. 1990 Sep-Oct;14(5):311-7.
CAS Number
– 549-56-4
Molecular Weight
– 422.50
SMILES
– O[C@H](C1=CC=NC2=C1C=C(OC)C=C2)[C@@]3([H])[N@](C[C@@H]4C=C)CC[C@H]4C3.O=S(O)(O)=O
Clinical Information
– Launched
Research Area
– Cancer; Infection; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Cytochrome P450;Parasite;Potassium Channel
Isoform
– Plasmodium
Pathway
– Anti-infection;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
