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Quinidine hydrochloride monohydrate
$60 – $66
Products Details
Product Description
– Quinidine hydrochloride monohydrate is an anti-arrythmic agent which is also a potent blocker of K+ channel with an IC50 of 19.9 μM.
Web ID
– HY-B1302
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H27ClN2O3
References
– [1]Wrighton DC, et al. Mechanism of inhibition of mouse Slo3 (KCa 5.1) potassium channels by quinine, quinidine and barium. Br J Pharmacol. 2015 Sep;172(17):4355-63.|[2]Cheng KI, et al. Application of quinidine on rat sciatic nerve decreases the amplitude and increases the latency of evoked responses. J Anesth. 2014 Aug;28(4):559-68.
CAS Number
– 6151-40-2
Molecular Weight
– 378.89
Compound Purity
– 99.61
SMILES
– C=C[C@H]1C[N@](CC[C@H]1C2)[C@@]2([H])[C@@H](O)C3=CC=NC4=CC=C(OC)C=C34.[H]Cl.[H]O[H]
Clinical Information
– Launched
Research Area
– Infection; Cardiovascular Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : 2.5 mg/mL (ultrasonic)
Target
– Parasite;Potassium Channel
Isoform
– Plasmodium
Pathway
– Anti-infection;Membrane Transporter/Ion Channel
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
