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Anethole trithione

$72$108

Products Details

Product Description

– Anethole trithione, a sulfur heterocyclic choleretic, is a bile secretion-stimulating agent. Anethole trithione enhances salivary secretion and increases mAChRs, and can be used for dry mouth research[1][2].

Web ID

– HY-B1223

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C10H8OS3

References

– [1]T Nagano, et al. Enhancement of salivary secretion and neuropeptide (substance P, alpha-calcitonin gene-related peptide) levels in saliva by chronic anethole trithione treatment. J Pharm Pharmacol. 2001 Dec;53(12):1697-702.|[2]Sheng Huang, et al. Synthesis, Characterization, and In Vivo Evaluation of Desmethyl Anethole Trithione Phosphate Prodrug for Ameliorating Cerebral Ischemia-Reperfusion Injury in Rats. ACS Omega. 2020 Feb 24;5(9):4595-4602.|[3]Y Ukai, et al. Chronic anethole trithione treatment enhances the salivary secretion and increases the muscarinic acetylcholine receptors in the rat submaxillary gland. Arch Int Pharmacodyn Ther. 1984 Oct;271(2):206-12.

CAS Number

– 532-11-6

Molecular Weight

– 240.36

Compound Purity

– 99.54

SMILES

– S=C1SSC(C2=CC=C(OC)C=C2)=C1

Clinical Information

– Launched

Research Area

– Cancer; Neurological Disease

Solubility

– DMSO : 12.5 mg/mL (ultrasonic)

Target

– mAChR

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Natural Products

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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