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Diphenylpyraline (hydrochloride)

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Products Details

Product Description

– Diphenylpyraline hydrochloride is a potent histamine H1 receptor antagonist. Diphenylpyraline hydrochloride acts as an orally active antihistamine agent with antimuscarinic and antiallergic effects. Diphenylpyraline hydrochloride can be used for the relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders in vivo.[1]

Web ID

– HY-B0970

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C19H24ClNO

References

– [1]Erik B Oleson, et al. Effects of the histamine H₁ receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward.|[2]Gennady B Lapa, et al. Diphenylpyraline, a histamine H1 receptor antagonist, has psychostimulant properties

CAS Number

– 132-18-3

Molecular Weight

– 317.85

Compound Purity

– 99.25

SMILES

– CN1CCC(OC(C2=CC=CC=C2)C3=CC=CC=C3)CC1.[H]Cl

Clinical Information

– Launched

Research Area

– Neurological Disease; Endocrinology

Solubility

– DMSO : ≥ 100 mg/mL|H2O : 100 mg/mL (ultrasonic)

Target

– Histamine Receptor

Isoform

– H1 Receptor

Pathway

– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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