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Medroxyprogesterone acetate
$66 – $79
Products Details
Product Description
– Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors[1].
Web ID
– HY-B0469
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H34O4
References
– [1]Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2008 Sep-Oct;61(1-2):171-80.|[2]Simoncini T, et al. Differential signal transduction of progesterone and medroxyprogesterone acetate in human endothelial cells. Endocrinology. 2004 Dec;145(12):5745-56. |[3]Smith D, et al. Pharmacokinetics and bioavailability of medroxyprogesterone acetate in the dog and the rat. Biopharm Drug Dispos. 1993 May;14(4):341-55. |[4]Bernardi F, et al. Progesterone and medroxyprogesterone acetate effects on central and peripheral allopregnanolone and beta-endorphin levels. Neuroendocrinology. 2006;83(5-6):348-59.
CAS Number
– 71-58-9
Molecular Weight
– 386.52
Compound Purity
– 99.88
SMILES
– CC(O[C@@]([C@]12C)(CC[C@@]1([H])[C@@](C[C@H](C)C3=CC4=O)([H])[C@]([C@]3(CC4)C)([H])CC2)C(C)=O)=O
Clinical Information
– Launched
Research Area
– Endocrinology; Cancer
Solubility
– DMSO : 10 mg/mL (ultrasonic)|Ethanol : 6.25 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : < 0.1 mg/mL
Target
– Androgen Receptor;Endogenous Metabolite;Glucocorticoid Receptor;Progesterone Receptor
Isoform
– Human Endogenous Metabolite
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
