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Diphenhydramine (hydrochloride)
$50 – $106
Products Details
Product Description
– Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2].
Web ID
– HY-B0303A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H22ClNO
References
– [1]Simons FE. H1-receptor antagonists. Comparative tolerability and safety. Drug Saf. 1994;10(5):350-380.|[2]Sadiq MW, et al. Diphenhydramine active uptake at the blood-brain barrier and its interaction with oxycodone in vitro and in vivo. J Pharm Sci. 2011;100(9):3912-3923.
CAS Number
– 147-24-0
Molecular Weight
– 291.82
Compound Purity
– 99.90
SMILES
– CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl
Clinical Information
– Launched
Research Area
– Inflammation/Immunology; Endocrinology; Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Target
– Bacterial;Endogenous Metabolite;Histamine Receptor
Isoform
– H1 Receptor
Pathway
– Anti-infection;GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
